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Craniofacial Embryogenetics and Development

Third Edition

Geoffrey H. Sperber (author) Steven M. Sperber (author)

ISBN: 9781607952824

Publication Date: Oct 2018

Format: Paperback

Genetic information gleaned from other mammalian species might aid in dissecting human embryology into comprehensible components to understand normal and abnormal development. This book is dedicated to this objective and will be invaluable to plastic and orofacial surgeons, otolaryngologists, orthodontists, paediatricians, speech pathologists, teratologists, embryologists, and anatomists.
£56.95

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  • Full Description
  • More Information
  • Table of Contents
  • Author Biography
  • Customer Reviews
The field of embryology has experienced a period of explosive growth since the previous edition of this book was published nearly a decade ago. The insights of genetic expression in determining the unfolding of the embryonic layers have revolutionised our understanding of some of the mechanisms of embryogenesis.

As implied by the title of the new edition, Craniofacial Embryogenetics and Development, genetics is linked with embryology in this text. Virtually all embryological development has an underlying genetic component, and the basic science of genetics is the key in uncovering the many mysteries of embryogenesis. The tools of molecular genetics have provided insights into developmental mechanisms that allow us the ability to identify transient regions of genetic expression patterns.

Unraveling the precise biochemical and mechanical interactions of discrete regions in the unfolding embryonic components remains a dauntingly-complex challenge to understanding the conversion of the genome into the phenome. The addition of genetic information gleaned from other mammalian species might aid in dissecting human embryology into comprehensible components to understand normal and abnormal development. This new edition is dedicated to this objective and will prove invaluable to plastic and orofacial surgeons, otolaryngologists, orthodontists, neonatal pediatricians, speech pathologists, teratologists, embryologists, and anatomists.

Key Features:
  • Provides clinicians with a basic background for assessing and treating craniofacial anomalies.
  • Describes recent technical advances in optical projection tomography, photoacoustic and 3D imaging, small-angle X-ray scattered (SAXS) tomography and morphometrics and their impact on embryogenetics.

Reviews

"Sperber and Sperber have produced an excellent third edition of Craniofacial Embryogenetics and Development. [...] There is no doubt that Craniofacial Embryogenetics and Development will remain a go-to textbook and reference for dental students, clinicians, and scientists alike for information about prenatal development of the entire craniofacial complex."
- David S. Carlson, American Journal of Orthodontics and Dentofacial Orthopedics

"It is well written and clear, and will remain a steadfast source of reference and learning for students in the future."
- David P. Rice, European Journal of Orthodontics
Pages 276
Dimensions 229 x 152
Date Published 30 Oct 2018
Publisher PMPH USA, Ltd
Subject/s Speech & language disorders & therapy   Anatomy   Dentistry   Plastic & reconstructive surgery   Otorhinolaryngology (ENT)   Medical genetics   Neonatal medicine   Embryology   Oral & maxillofacial surgery  
  • Preface.
  • Preface to Previous Edition.
  • SECTION I: General Embryology
  • Chapter 1: Mechanisms of Embryology
  • Chapter 2: Early Embryonic Development
  • Chapter 3: Early Orofacial Development
  • Chapter 4: Pharyngeal Arches
  • Chapter 5: Pharyngeal Pouches and Pharyngeal Grooves
  • Chapter 6: Bone Development and Growth
  • SECTION II: Craniofacial Development
  • Introduction
  • Chapter 7: Calvaria
  • Chapter 8: Cranial Base
  • Chapter 9: Facial Skeleton
  • Chapter 10: Palate
  • Chapter 11: Paranasal Sinuses
  • Chapter 12: Mandible
  • Chapter 13: Temporomandibular Joint
  • Chapter 14: Skull Growth: Sutures and Cephalometrics
  • Chapter 15: Tongue and Tonsils
  • Chapter 16: Salivary Glands
  • Chapter 17: Muscle Development
  • Chapter 18: Special Sense Organs
  • Chapter 19: Development of the Dentition (Odontogenesis)
  • Chapter 20: Craniofacial Disorders with Known Single Gene Mutations
  • Glossary.
  • Index.
Geoffrey H. Sperber, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.

Steven M. Sperber, Department of Genetics and Genomic Sciences, Associate Director, The Mount Sinai Genetic Testing Laboratory, Icahn School of Medicine at Mount Sinai, Mount Sinai Hospital, New York, USA.

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