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Medical Cannabis and the Effects of Cannabinoids on Fighting Cancer, Multiple Sclerosis, Epilepsy, Parkinson's, and Other Neurodegenerative Diseases

Rana R. Zeine

Research on the therapeutic efficacy of cannabinoids has demonstrated that cannabidiol (CBD), either alone or in 1:1 mixtures with delta-9-tetrahydrocannabinol (THC), can effectively treat animals in experimental models of neuroinflammatory, demyelinative, neurodegenerative, neuropsychiatric, and neoplastic diseases. Short-term, small-scale, human cohorts, observational studies, randomized, non-randomized, placebo-controlled, and uncontrolled clinical trials have provided low-certainty and moderate-certainty evidence that medical marijuana can reduce spasticity, neuropathic pain, neuroinflammation, anxiety, sleep disturbance, urinary bladder dysfunction, frequency and duration of seizure, tumor size, and metastasis as well as promote overall cancer survival. Medical Cannabis and the Effects of Cannabinoids on Fighting Cancer, Multiple Sclerosis, Epilepsy, Parkinson's, and Other Neurodegenerative Diseases presents the findings from clinical and basic medical scientists who are investigating the cellular and molecular mechanisms of cannabinoid-mediated inhibition of innate and adaptive immune responses, mobilization of myeloid-derived immunosuppressive cells, enhancement of neuroprotection, facilitation of oligodendrocyte survival, promotion of CNS progenitor cell differentiation to support regeneration and remyelination, arrest of tumor cell proliferation, decrease in tumor cell adhesion, disruption of tumor angiogenesis, inhibition of endothelial cells, and prevention of cancer metastasis by inhibition of cell migration. The chapters further discuss pharmacologic challenges and precisely how the delicate balance between the opposing effects of various types of cannabinoid receptors can be controlled by manipulating specific membrane channels and signaling pathways to achieve favorable long-term clinicopathologic outcomes in oncology and neurology. Covering topics such as neurodegenerative diseases, spectroscopic applications, and ethical issues, this premier reference source is an essential resource for medical professionals, pharmacists, hospital administrators, government officials, students and faculty of higher education, librarians, researchers, and academicians.

Format: Hardback
ISBN: 9781668456521
Publication Date: Mar 2023
Availability: In Stock - Despatched Within 5 Working Days

Cannabis sativa Cultivation, Production, and Applications in Pharmaceuticals and Cosmetics

Rafiq Lone

Cannabis sativa has a long history; however, it has not been fully exploited for its beneficial uses. This plant can solve many present challenges, including challenges found in the pharmaceutical and cosmetic industries. Bioprospecting of this very important plant can generate economic upliftment of weaker sections of society and states if properly used under rules and regulations. Cannabis sativa Cultivation, Production, and Applications in Pharmaceuticals and Cosmetics discusses in detail the current research conducted in the area of Cannabis sativa in order to make it more useful and sustainable for the future. It further focuses on the exploration of Cannabis sativa phytoconstituents in various fields, especially in the pharmaceutical and cosmetic industries. Covering topics such as bioactive properties, molecular modeling, and soil pollutants, this premier reference source is an excellent resource for pharmacologists, pharmacists, health professionals, food scientists, agricultural scientists, botanists, chemists, students and educators of higher education, librarians, researchers, and academicians.

Format: Hardback
ISBN: 9781668457184
Publication Date: Mar 2023
Availability: In Stock - Despatched Within 5 Working Days

Rapid Innovation and Development in the Global Cannabis Market

Pfano Mashau

In recent years, the public has become acquainted with the benefits of cannabis following the legalization of the use of cannabis-based products such as medicinal products, skincare and body products, CBD, and other developments. This has resulted in an economically viable industry that requires high-level investigation in order for countries to fully benefit from it. Rapid Innovation and Development in the Global Cannabis Market considers the recent innovations and developments in the global cannabis market, captures the effects of different policies governing the industry, and documents products and processes innovations. Covering topics such as market potential, government intervention, and sustainable models, this reference work is ideal for government officials, policymakers, industry professionals, researchers, scholars, practitioners, academicians, instructors, and students.

Format: Hardback
ISBN: 9781668463468
Publication Date: Jan 2023
Availability: In Stock - Despatched Within 5 Working Days